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NCLEX-RN: Safety, Infection Control and Isolation Precautions — quiz

20 multiple-choice questions covering Standard Precautions, Transmission-Based Precautions, Contact Precautions, Droplet Precautions, Airborne Precautions. One answer each; you get a score at the end and the explanation for every question. No account needed.

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Updated 2026-11-03. Keys 1–4 pick an answer, Enter moves on. Redo it any time, in order or shuffled.

The questions

Answers and explanations are shown after you finish.

  1. Standard Precautions

    A nurse is preparing to care for a newly admitted patient with no known infections. Which set of precautions must the nurse apply to this patient, as with every patient in the facility?

    • Airborne precautions
    • Contact precautions
    • Standard precautions
    • Reverse isolation
  2. Transmission-Based Precautions

    A nurse is reviewing isolation categories added on top of standard precautions based on how an organism spreads. Which three categories make up transmission-based precautions?

    • Enhanced, barrier, and standard precautions
    • Sterile, clean, and dirty technique
    • Contact, droplet, and airborne precautions
    • Universal, reverse, and protective isolation
  3. Contact Precautions

    A nurse enters the room of a patient with a draining MRSA wound to help reposition the patient, with no risk of splashing. What PPE is the minimum required for this task?

    • Gown and gloves
    • N95 respirator and gown
    • Surgical mask and gloves
    • Gown, gloves, and goggles
  4. Contact Precautions

    After removing gloves while caring for a patient with C. difficile diarrhea, which hand hygiene method should the nurse use?

    • Either hand rub or soap and water
    • Antiseptic foam
    • Soap and water
    • Alcohol-based hand rub
  5. Droplet Precautions

    A nurse is caring for a patient with suspected bacterial meningitis on droplet precautions. Within what distance of the patient must the nurse wear a surgical mask?

    • 10 feet
    • 6 feet
    • Any distance within the room
    • 3 feet
  6. Droplet Precautions

    A nurse must transport a patient on droplet precautions to the radiology department. What is required during transport?

    • The client should be transported in a negative-pressure unit
    • No special precautions are needed
    • The client should wear a surgical mask
    • The nurse should wear an N95 respirator
  7. Airborne Precautions

    Which piece of PPE must be individually fit-tested to the nurse before being used to enter an airborne precautions room?

    • Face shield
    • Isolation gown
    • N95 respirator
    • Surgical mask
  8. Airborne Precautions

    Which of the following illnesses is spread by small droplet nuclei that remain suspended in air, requiring airborne precautions?

    • Influenza
    • Pertussis
    • MRSA wound infection
    • Measles
  9. Airborne Precautions

    A client with active tuberculosis develops a new draining MRSA wound infection. How should the nurse manage precautions for this client?

    • Airborne precautions only, since TB is the more serious condition
    • Droplet and contact precautions
    • Contact precautions only, since the wound is now draining
    • Both airborne and contact precautions simultaneously
  10. PPE Donning & Doffing

    When a nurse exits an isolation room and removes PPE in sequence, which item should be removed last?

    • Gloves
    • Goggles or face shield
    • Mask or respirator
    • Gown
  11. PPE Donning & Doffing

    Why does a nurse perform hand hygiene immediately after removing gloves, even before removing the rest of the PPE?

    • It sanitizes the gloves for reuse later
    • Alcohol rub kills pathogens remaining on the gown
    • It is only required after the final piece of PPE is removed
    • It minimizes transfer of contamination from the gloves to other PPE or surfaces
  12. Hand Hygiene

    According to the WHO '5 Moments for Hand Hygiene,' hand hygiene is required before touching a patient, before an aseptic procedure, after a body fluid exposure risk, after touching a patient, and at which other time?

    • After entering the patient care unit
    • Before entering the building
    • After completing documentation
    • After touching the patient's surroundings
  13. Sharps Safety

    A nurse experiences a needlestick injury from a used needle. What should the nurse do first?

    • Report to the supervisor before doing anything else
    • Squeeze the wound to force blood out
    • Wash the area immediately with soap and water
    • Apply an alcohol swab and continue the task
  14. Restraints

    A client becomes combative and the nurse is considering applying restraints. What must be attempted first?

    • Apply soft wrist restraints right away for safety
    • Administer a sedating medication immediately
    • Try least restrictive alternatives such as de-escalation first
    • Obtain a PRN restraint order from the provider
  15. Restraints

    In a true emergency where a client is an immediate danger, can a nurse apply restraints before obtaining a provider's order?

    • No, a provider's order is always required before applying restraints
    • Yes, but a time-limited provider order must be obtained within a short specified period
    • No, only a psychiatrist may authorize emergency restraints
    • Yes, and a provider's order is never required afterward
  16. Fire Safety

    Using the RACE mnemonic during a hospital fire, what action should the nurse take first?

    • Activate the fire alarm
    • Rescue clients in immediate danger
    • Confine the fire by closing doors
    • Extinguish the fire with an extinguisher
  17. Fire Safety

    During evacuation of clients in a hospital fire, which of the following should the nurse avoid using?

    • Evacuation sleds
    • Elevators
    • Fire doors
    • Stairwells
  18. Medication Safety

    Before administering medication, a nurse must verify the right patient using two identifiers. Which combination is acceptable?

    • Full name and date of birth
    • First name and room number
    • Diagnosis and allergy band
    • Room number and bed number
  19. Error Reporting

    After completing an incident report for a medication error, where should the nurse document that the report was filed?

    • Nowhere in the medical record, since it is kept separate
    • In the discharge summary
    • In the nursing progress notes
    • In the medication administration record
  20. NCLEX Client Needs Categories

    On the NCLEX-RN test plan, which of the following is NOT one of the four major Client Needs categories?

    • Infection Control Management
    • Health Promotion and Maintenance
    • Safe and Effective Care Environment
    • Physiological Integrity
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